(Patents no..: EP 1 142 571 + US 6,689,299 B2)
..is a formulation, in which creatine is embedded in Isomalt and HPMC by means of a patented process. The creatine particles prediluted in said polymer matrix and present and amorphous state are released slowly over an extended period of time to improve the stability and availability.
Diagram of the patented manufacturing process
Why is creatine important?
Creatine is a naturally occurring substance. Creatine recharges the energy reservoir of all of the body’s cells in split seconds (AMP -> ATP) and is used up in the process. The average creatine reservoir of an adult is approx. 100-120 g. Creatine is absorbed primarily through the consumption of meat and fish, which helps maintain the body’s creatine reservoir in balance. As a result, the creatine values of vegetarians are significantly lower.
People suffering from a condition known as creatine deficiency syndrome exhibit serious neurological and neuromuscular pathologies, e.g. poorly developed muscles, increased risk of osteoporosis, inability to learn to talk, epilepsy, autism, and mental disabilities.
Creatine monohydrate as pure substance
Creatine monohydrate is fairly instable, quickly breaks down to creatine in an aqueous environment and is thus eliminated by the kidneys without achieving any effect. The recommended daily doses as nutritional supplement are 5-15 g.
Wallimann et al. Schweiz Med Forum, 2008;8(30-31):550-551 [Swiss Med. Forum, 2008;8(30-31].